Sherlock Holmes: A Game of Shadows (2011) In 1891, Irene Adler delivers a package to Dr. Hoffmanstahl, payment for a letter he was to deliver. Hoffmanstahl opens the package, triggering a hidden bomb that is prevented from detonating by the intervention of Sherlock Holmes. Holmes takes the letter while Adler and Hoffmanstahl escape. Holmes finds Hoffmanstahl assassinated moments later. Adler meets with Professor Moriarty to explain the events, but Moriarty, deeming her position compromised by her love for Holmes, poisons and kills her....